Download Adhesion Molecules (Modern Insights Into Disease from by Victor R. Preedy PDF

By Victor R. Preedy

This ebook covers the constitution and category of adhesion molecules when it comes to signaling pathways and gene expression. It discusses immunohistochemical localization, neutrophil migration, and junctional, practical, and inflammatory adhesion molecules in pathologies reminiscent of leukocyte decompression affliction and ischemia reperfusion harm. Highlighting the clinical purposes of present learn, chapters conceal diabetes, weight problems, and metabolic syndrome; hypoxia; kidney disorder; smoking, atrial traumatic inflammation, and middle ailment, the mind and dementia; and tumor proliferation. eventually, it appears to be like at molecular imaging and bioinformatics, high-throughput applied sciences, and chemotherapy.

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Annu. Rev. Immunol. 25: 619-647. Morishita, H. and T. Yagi. 2007. Protocadherin family: diversity, structure, and function. Curr. Opin. Cell. Biol. 19: 584-592. Parisini, E. G. H. B. H. Wang. 2007. The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism. J. Mol. Biol. 373: 401-411. D. P. Chen, F. Bahna, B. Honig, and L. Shapiro. 2003. Cadherin-mediated cell-cell adhesion: sticking together as a family. Curr. Opin. Struct.

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2008. Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow. Blood 111: 1989-1998. Shimaoka, M. and J. A. Springer. 2002. Conformational regulation of integrin structure and function. Annu. Rev. Biophys. Biomol. Struct. 31: 485-516. Shimaoka, M. and T. H. Liu, Y. Yang, Y. D. Jun, A. McCormack, R. Zhang, A. Joachimiak, J. H. A. Springer. 2003. Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation.

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